BDBM202654 US9242957, QJ-III-07

SMILES Fc1cccc(COC[C@H]2NCC[C@@H]2COc2cccc(NC(=N)c3cccs3)c2)c1

InChI Key InChIKey=HEEDPPMMSPLXOE-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 202654   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

US Patent
LigandPNGBDBM202654(US9242957, QJ-III-07)
Affinity DataKi:  68.4nMAssay Description:The compounds were evaluated for in vitro inhibition against three NOS isozymes: rat nNOS, bovine eNOS and marine iNOS using known literature methods...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details
US Patent

TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

US Patent
LigandPNGBDBM202654(US9242957, QJ-III-07)
Affinity DataKi:  5.89E+3nMAssay Description:The compounds were evaluated for in vitro inhibition against three NOS isozymes: rat nNOS, bovine eNOS and marine iNOS using known literature methods...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details
US Patent

TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

US Patent
LigandPNGBDBM202654(US9242957, QJ-III-07)
Affinity DataKi:  6.17E+3nMAssay Description:The compounds were evaluated for in vitro inhibition against three NOS isozymes: rat nNOS, bovine eNOS and marine iNOS using known literature methods...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details
US Patent