BDBM204302 US9242996, 381

SMILES CNC[C@@H](NC(=O)c1ccc(cc1F)-c1nc(cnc1N)[C@H]1CC[C@H](O)CC1)c1cccc(Br)c1

InChI Key InChIKey=AAKGNGAYAIRPPC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 204302   

TargetMitogen-activated protein kinase 1(Human)
Novartis

US Patent
LigandPNGBDBM204302(US9242996, 381)
Affinity DataIC50: 0.0209nMpH: 7.5Assay Description:Compound potency against activated ERK2 was determined using a kinase assay that measures ERK2-catalyzed phosphorylation of biotinylated ERKtide pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2016
Entry Details
US Patent