BDBM204832 US9242977, 48

SMILES CCNc1ncc(s1)-c1ccc(Oc2ncc(NC(=O)Nc3cc(cnc3Oc3ccccc3)C(F)(F)F)cn2)cc1

InChI Key InChIKey=KBYMDDHXJPDQEG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 204832   

LigandPNGBDBM204832(US9242977, 48)
Affinity DataIC50: 120nMpH: 7.5Assay Description:TrkA-inhibiting activity was measured according to the following method using LanthaScreen kinase assay reagents (Invitrogen; Fluorescein-Poly GT, La...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details
Go to US Patent

LigandPNGBDBM204832(US9242977, 48)
Affinity DataIC50: 10nMAssay Description:TrkA kinase-inhibiting activity in cell systems was measured using CHO-K1 cells expressing human TrkA and NFAT-bla (CellSenser TrkA-NFAT-bla CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details
Go to US Patent