BDBM204848 US9242977, 85-117

SMILES CCCNc1ncc(s1)-c1ccc(Oc2ncc(NC(=O)Nc3cc(ccc3Cl)C(F)(F)F)cn2)cc1

InChI Key InChIKey=VMWCQUXKURWYMM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 204848   

LigandPNGBDBM204848(US9242977, 85-117)
Affinity DataIC50: 20nMpH: 7.5Assay Description:TrkA-inhibiting activity was measured according to the following method using LanthaScreen kinase assay reagents (Invitrogen; Fluorescein-Poly GT, La...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details
Go to US Patent

LigandPNGBDBM204848(US9242977, 85-117)
Affinity DataIC50: 2nMAssay Description:TrkA kinase-inhibiting activity in cell systems was measured using CHO-K1 cells expressing human TrkA and NFAT-bla (CellSenser TrkA-NFAT-bla CHO-K1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details
Go to US Patent