BDBM204926 1-{2-oxo-2-[(1R,3S,5R)-3-{[1-(2,2,2-trifluoroethyl)-1H-pyrazol-3-yl]carbamoyl}-2-azabicyclo[3.1.0]hexan-2-yl]ethyl}-1H-indazole-3-carboxamide::US9550755, example 1

SMILES NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2ccn(CC(F)(F)F)n2)c2ccccc12

InChI Key InChIKey=IDHWYPJSSBBAHQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 204926   

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM204926(1-{2-oxo-2-[(1R,3S,5R)-3-{[1-(2,2,2-trifluoroethyl...)
Affinity DataIC50: 64nMpH: 7.5 T: 2°CAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
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Date in BDB:
8/28/2018
Entry Details
US Patent