BDBM20518 6-(4-tert-butylphenyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)pyrimidin-4-amine::Pyrimidine derivative, 17

SMILES CC(C)(C)c1ccc(cc1)-c1cc(Nc2ccc3OCCOc3c2)ncn1

InChI Key InChIKey=VLTDPHWBZLQDBR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 20518   

LigandPNGBDBM20518(6-(4-tert-butylphenyl)-N-(2,3-dihydro-1,4-benzodio...)
Affinity DataIC50: 51nMpH: 7.4 T: 2°CAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20518(6-(4-tert-butylphenyl)-N-(2,3-dihydro-1,4-benzodio...)
Affinity DataIC50: 120nMpH: 7.4 T: 2°CAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20518(6-(4-tert-butylphenyl)-N-(2,3-dihydro-1,4-benzodio...)
Affinity DataIC50: 270nMAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20518(6-(4-tert-butylphenyl)-N-(2,3-dihydro-1,4-benzodio...)
Affinity DataIC50: 680nMAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2008
Entry Details Article
PubMed