BDBM205241 US9249123, 102

SMILES CN1CCNC(C1=O)c1ccc(Nc2nc(cn(C)c2=O)-c2cccc(N3Cc4cc(sc4C3=O)C(C)(C)C)c2C)cc1

InChI Key InChIKey=HNIGJEPWBMTNQG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 205241   

TargetTyrosine-protein kinase BTK(Human)
Genentech

US Patent
LigandPNGBDBM205241(US9249123, 102)
Affinity DataIC50: 11.5nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent