BDBM205242 BDBM205248::US9249123, 104

SMILES CN1CCNC(=O)C1c1ccc(Nc2nc(cn(C)c2=O)-c2cccc(N3Cc4cc(sc4C3=O)C(C)(C)C)c2C)cc1

InChI Key InChIKey=MSVIUHGKRXUQLL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 205242   

TargetTyrosine-protein kinase BTK(Human)
Genentech

US Patent
LigandPNGBDBM205242(BDBM205248 | US9249123, 104)
Affinity DataIC50: 24.7nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Genentech

US Patent
LigandPNGBDBM205242(BDBM205248 | US9249123, 104)
Affinity DataIC50: 95nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent