BDBM205246 US9249123, 130

SMILES CN1CCN(C)C(=O)[C@@H]1c1ccc(Nc2nc(cn(C)c2=O)-c2ccc(F)c(N3Cc4cc(sc4C3=O)C(C)(C)C)c2F)cc1

InChI Key InChIKey=GLUAAPDLCNUCRL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 205246   

TargetTyrosine-protein kinase BTK(Human)
Genentech

US Patent
LigandPNGBDBM205246(US9249123, 130)
Affinity DataIC50: 33.7nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent