BDBM20530 N-[6-(4-tert-butylphenyl)pyrimidin-4-yl]quinolin-7-amine::Pyrimidine derivative, 78

SMILES CC(C)(C)c1ccc(cc1)-c1cc(Nc2ccc3cccnc3c2)ncn1

InChI Key InChIKey=OSNBQAGGOQNXAP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 20530   

LigandPNGBDBM20530(N-[6-(4-tert-butylphenyl)pyrimidin-4-yl]quinolin-7...)
Affinity DataIC50: 1.90nMpH: 7.4 T: 2°CAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20530(N-[6-(4-tert-butylphenyl)pyrimidin-4-yl]quinolin-7...)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20530(N-[6-(4-tert-butylphenyl)pyrimidin-4-yl]quinolin-7...)
Affinity DataIC50: 6.90nMAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20530(N-[6-(4-tert-butylphenyl)pyrimidin-4-yl]quinolin-7...)
Affinity DataIC50: 22nMAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2008
Entry Details Article
PubMed