BDBM205497 Cytotoxic conjugates, 15
SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)NCc3ccc(CNC(=O)CCC(=O)O[C@H]4C5COC(=O)[C@H]5[C@@H](c5cc(OC)c(OC)c(OC)c5)c5cc6OCOc6cc45)cc3)c2c1
InChI Key InChIKey=CVONHWSXJQMVEI-HSIYWZETSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 205497
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt Institute of Chemical Biology, Vanderbilt University School of Medicine
Vanderbilt Institute of Chemical Biology, Vanderbilt University School of Medicine
Affinity DataIC50: 180nMAssay Description:Each molecule was evaluated for its ability to inhibit purified mouse COX-2 or ovine COX-1 using a previously described assay. [Kalgutkar et al, J. M...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt Institute of Chemical Biology, Vanderbilt University School of Medicine
Vanderbilt Institute of Chemical Biology, Vanderbilt University School of Medicine
Affinity DataIC50: >2.50E+4nMAssay Description:Each molecule was evaluated for its ability to inhibit purified mouse COX-2 or ovine COX-1 using a previously described assay. [Kalgutkar et al, J. M...More data for this Ligand-Target Pair