BDBM206012 US9255103, 13

SMILES C[C@@H]%10Cc1c([nH]c2ccccc12)[C@@H](c9cnc(O[C@@H]8C[C@@H](C(=O)N7CCC(N6Cc5cc4c(=O)n(C3CCC(=O)NC3=O)c(=O)c4cc5C6)CC7)C8)nc9)N%10CC(F)F

InChI Key InChIKey=KEVMXEVGWMIWSP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206012   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 206012BDBM206012(6-(1-((1R,3r)-3-((5-((1R,3R)-2- (2,2-difluoroethyl...)
Affinity DataIC50: 275nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent