BDBM206015 US9255103, 16::US9255103, 40::US9255103, 41

SMILES CC1CN(Cc2cc(COc3ccccc3)nn12)C(=O)c1ccc(F)cc1

InChI Key InChIKey=WPYXCCUZWTVDCS-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 206015   

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

US Patent
LigandPNGBDBM206015(US9255103, 16 | US9255103, 40 | US9255103, 41)
Affinity DataEC50:  162nMpH: 7.4Assay Description:HEK cells transfected with the human mGluR5a receptor (H10H cell line) were plated at 15,000 cells/well in clear-bottomed poly-D-lysine-coated assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

US Patent
LigandPNGBDBM206015(US9255103, 16 | US9255103, 40 | US9255103, 41)
Affinity DataEC50:  172nMpH: 7.4Assay Description:HEK cells transfected with the human mGluR5a receptor (H10H cell line) were plated at 15,000 cells/well in clear-bottomed poly-D-lysine-coated assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

US Patent
LigandPNGBDBM206015(US9255103, 16 | US9255103, 40 | US9255103, 41)
Affinity DataEC50:  708nMpH: 7.4Assay Description:HEK cells transfected with the human mGluR5a receptor (H10H cell line) were plated at 15,000 cells/well in clear-bottomed poly-D-lysine-coated assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details
US Patent