BDBM206024 US9255103, 25

SMILES COc6cc(N5CCC(CN4CCN3c2cc(F)c(C(=O)N[C@H]1CCC(=O)NC1=O)cc2OC[C@@H]3C4)CC5)ccc6[C@@H]9c8[nH]c7ccccc7c8C[C@@H](C)N9CC(F)F

InChI Key InChIKey=UOTHEUCAUHMAHR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206024   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 206024BDBM206024((S)-3-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-met...)
Affinity DataIC50: 2.75E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent