BDBM206027 US9255103, 28

SMILES COc7cc(N6CCC(CN1CCC5(CC1)COc4cc3C(=O)N(C2CCC(=O)NC2=O)Cc3cc45)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(F)F

InChI Key InChIKey=NKQVWHXQWZMTBQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206027   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 206027BDBM206027(3-(1'-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-met...)
Affinity DataIC50: 275nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent