BDBM206046 US9255103, 47::US9255103, 48

SMILES COc7cc(N6CCC(CN5CCN4c3cc2CN([C@@H]1CCC(=O)NC1=O)C(=O)c2cc3OC[C@H]4C5)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(F)F

InChI Key InChIKey=WKOIRAKZQGBWCW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206046   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 206046BDBM206046((R)-3-((R)-3-((1-(4-((1R,3R)-2-(2,2- difluoroethyl...)
Affinity DataIC50: 50nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent