BDBM206048 US9255103, 49::US9255103, 50

SMILES COc7cc(N6CCC(CN5CCN4c3ccc2C(=O)N([C@H]1CCC(=O)NC1=O)Cc2c3OC[C@H]4C5)CC6)ccc7[C@@H]%10c9[nH]c8ccccc8c9C[C@@H](C)N%10CC(C)(C)F

InChI Key InChIKey=ONGKHRMQCCVSPT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 206048   

TargetEstrogen receptor [282-595](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 206048BDBM206048((S)-3-((R)-7-((1-(4-((1R,3R)-2-(2-fluoro- 2-methyl...)
Affinity DataIC50: 10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 206048BDBM206048((S)-3-((R)-7-((1-(4-((1R,3R)-2-(2-fluoro- 2-methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent