BDBM206052 US9255103, 53

SMILES COc6cc(N5CCC(CN4CCN3c2ccc(C(=O)NC1CCC(=O)NC1=O)nc2OC[C@H]3C4)CC5)ccc6[C@@H]9c8[nH]c7ccccc7c8C[C@@H](C)N9CC(F)F

InChI Key InChIKey=VPOZGRAOIJNXPP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 206052   

TargetEstrogen receptor [282-595](Homo sapiens (Human))
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206052BDBM206052((4aR)-3-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-m...)
Affinity DataIC50: 10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206052BDBM206052((4aR)-3-((1-(4-((1R,3R)-2-(2,2- difluoroethyl)-3-m...)
Affinity DataIC50: 2.75E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent