BDBM206056 US9255103, 57

SMILES COc5cc(N4CCC(CN3CCN(c2ccc(C(=O)N[C@H]1CCC(=O)NC1=O)nc2)CC3)CC4)ccc5[C@@H]8c7[nH]c6ccccc6c7C[C@@H](C)N8CC(F)F

InChI Key InChIKey=HOFPALVKNDSITL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 206056   

TargetEstrogen receptor [282-595](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 206056BDBM206056(5-(4-((1-(4-((1R,3R)-2-(2,2-difluoroethyl)- 3-meth...)
Affinity DataIC50: 10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 206056BDBM206056(5-(4-((1-(4-((1R,3R)-2-(2,2-difluoroethyl)- 3-meth...)
Affinity DataIC50: 5.00E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent