BDBM206768 US9260448, 74

SMILES C[C@@H]%10Cc1c([nH]c2ccccc12)[C@@H](c9cnc(N3CCC8(CC3)C[C@@H](CN7CCN6c5ccc(C(=O)N[C@H]4CCC(=O)NC4=O)nc5OC[C@H]6C7)CO8)nc9)N%10CC(F)F

InChI Key InChIKey=QWJZAXKOFFQJEB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 206768   

TargetEstrogen receptor [282-595](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 206768BDBM206768((R)-3-(((S)-8-(5-((1R,3R)-2-(2,2- difluoroethyl)-3...)
Affinity DataIC50: 10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 206768BDBM206768((R)-3-(((S)-8-(5-((1R,3R)-2-(2,2- difluoroethyl)-3...)
Affinity DataIC50: 2.75E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent