BDBM206867 US9249163, 8

SMILES [O-]C(=O)c1cc(\C=C\c2cn3ccnc(N4CCOCC4)c3n2)nc2ccccc12

InChI Key InChIKey=YMCNDWSLVNYLPN-UHFFFAOYSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 206867   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM206867(US9249163, 8)
Affinity DataIC50: 2nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6×Hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2016
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM206867(US9249163, 8)
Affinity DataIC50: 9nMpH: 7.8Assay Description:Rat recombinant PDE10a (rPDE10a) was expressed in Sf9 cells using a recombinant rPDE10a baculovirus construct. Cells were harvested after 48 h of inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2016
Entry Details
US Patent