BDBM207582 US10501467, Example 27::US9260440, 27::US9617273, Example 27

SMILES CC1(C)CC2=NNC(=O)c3cc(F)cc4[nH]c(c2c34)C1O

InChI Key InChIKey=TVEKOZNCZJHWEH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 207582   

TargetPoly [ADP-ribose] polymerase 1(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 207582BDBM207582(US9260440, 27 | US9617273, Example 27 | US10501467...)
Affinity DataIC50: 11nMpH: 8.0Assay Description:PARP-1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP-1 was pre-incuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/9/2017
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 207582BDBM207582(US9260440, 27 | US9617273, Example 27 | US10501467...)
Affinity DataIC50: 11nMAssay Description:PARP-1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP-1 was pre-incuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 207582BDBM207582(US9260440, 27 | US9617273, Example 27 | US10501467...)
Affinity DataIC50: 1.10E+4nMAssay Description:PARP-1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP-1 was pre-incuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent