BDBM208402 US9266835, 80

SMILES Clc1ccc(cc1)C(c1ccc(Cl)cc1)c1ccc2[nH]c(=O)cc(NC3CCN(CC3)S(=O)(=O)c3ccccc3)c2c1

InChI Key InChIKey=SPSDQCVVNWOHJA-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 208402   

TargetCannabinoid receptor 1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM208402(US9266835, 80)
Affinity DataEC50:  14nMAssay Description:Inverse agonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM208402(US9266835, 80)
Affinity DataEC50:  14nMAssay Description:The following mixtures and buffer solutions were prepared: (a) Buffer 1: HBSS (Mediatech Cat#21-023-CV) with 5 mM HEPES (1 mM stock, Gibco BRL Cat#15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2017
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM208402(US9266835, 80)
Affinity DataEC50: >1.00E+4nMAssay Description:The following mixtures and buffer solutions were prepared: (a) Buffer 1: HBSS (Mediatech Cat#21-023-CV) with 5 mM HEPES (1 mM stock, Gibco BRL Cat#15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2017
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM208402(US9266835, 80)
Affinity DataEC50: >1.00E+4nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed