BDBM20842 3-[2-(pyridin-4-yl)-1,3-thiazol-4-yl]-1,2-dihydroquinolin-2-one::quinolin-2(1H)-one derivative, 3

SMILES O=c1[nH]c2ccccc2cc1-c1csc(n1)-c1ccncc1

InChI Key InChIKey=DPFVGQNGSOMJSY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20842   

TargetCyclin-dependent kinase 5(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM20842(3-[2-(pyridin-4-yl)-1,3-thiazol-4-yl]-1,2-dihydroq...)
Affinity DataIC50: 54nMAssay Description:Inhibition of human CDK5More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM20842(3-[2-(pyridin-4-yl)-1,3-thiazol-4-yl]-1,2-dihydroq...)
Affinity DataIC50: 54nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed