BDBM208450 US9266869, 8

SMILES Cc1ccc(F)c(NC(=O)Nc2cccc(c2)C#Cc2cncc(c2)C(=O)N=S(C)(C)=O)c1

InChI Key InChIKey=NYWWQVWITWVVAU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 208450   

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM208450(US9266869, 8)
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM208450(US9266869, 8)
Affinity DataIC50: 10nMT: 2°CAssay Description:Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Allergan

US Patent
LigandPNGBDBM208450(US9266869, 8)
Affinity DataIC50: 28nMT: 2°CAssay Description:Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of PDGF-induced increases in intracellular calcium l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
US Patent