BDBM208474 US9266869, 32
SMILES COC(=O)CCCC[S@](C)(=O)=NC(=O)c1cnc(N)c(c1)C#Cc1cccc(NC(=O)c2occc2C)c1
InChI Key InChIKey=SXGZAYZKUGJQPT-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 208474
Affinity DataIC50: 1nMT: 2°CAssay Description:Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium l...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMpH: 7.4 T: 2°CAssay Description:Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMT: 2°CAssay Description:Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of PDGF-induced increases in intracellular calcium l...More data for this Ligand-Target Pair