BDBM209032 US9243038, 6a (cis olefin)::US9243038, 6b (trans olefin)
SMILES NC(=O)CC[C@@H]1NC(=O)\C=C\C(=O)N[C@@H](CCCCNC(=O)[C@@H](Cc2ccc(cc2)C(=O)c2ccccc2)NC(=O)[C@H](CC2CCCCC2)NC1=O)C(N)=O
InChI Key InChIKey=NBNYXFCHNYKOOT-JCBKMTHPSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 209032
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 5.60E+3nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 90nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 60nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair