BDBM20980 N-butyl-8-(2,6-dimethoxypyridin-3-yl)-N-ethyl-2-methyl-5,6,7,8-tetrahydropteridin-4-amine::Pteridine, 2d

SMILES CCCCN(CC)c1nc(C)nc2N(CCNc12)c1ccc(OC)nc1OC

InChI Key InChIKey=OKRBKOWKTDTHMA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20980   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20980(N-butyl-8-(2,6-dimethoxypyridin-3-yl)-N-ethyl-2-me...)
Affinity DataIC50: 9.90nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed