BDBM20981 4-(4,5-dimethoxy-2-methylphenyl)-8-[(2-methoxyethyl)(propyl)amino]-6-methyl-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-2-one::Pyridopyrazinone, 3a

SMILES CCCN(CCOC)c1cc(C)nc2N(CC(=O)Nc12)c1cc(OC)c(OC)cc1C

InChI Key InChIKey=USWMKGDQSNWJEC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20981   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20981(4-(4,5-dimethoxy-2-methylphenyl)-8-[(2-methoxyethy...)
Affinity DataIC50: 43nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed