BDBM209855 US9273052, 3::US9566277, 3

SMILES COC(=O)c1nc(n2CCN(Cc12)C(=O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F)C(F)(F)F

InChI Key InChIKey=HIIJWJUIQSSMSB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209855   

TargetPoly [ADP-ribose] polymerase 1(Human)
Jiangsu Hansoh Pharmaceutical

US Patent
LigandPNGBDBM209855(US9273052, 3 | US9566277, 3)
Affinity DataIC50: 52nMT: 2°CAssay Description:The tested compounds were dissolved in dimethylsulfoxide and then diluted with 1x buffer to the concentration desired in the experiment. 25 uL of a 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Jiangsu Hansoh Pharmaceutical

US Patent
LigandPNGBDBM209855(US9273052, 3 | US9566277, 3)
Affinity DataIC50: 52nMT: 2°CAssay Description:he assay described below is to determine the activity of the compounds of the present invention for inhibiting the enzyme activity of PARP by using t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent