BDBM20990 1-(4-{8-[butyl(ethyl)amino]-6-methyl-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-4-yl}-3-methylphenyl)ethan-1-one::Pyridopyrazine, 5b

SMILES CCCCN(CC)c1cc(C)nc2N(CCNc12)c1ccc(cc1C)C(C)=O

InChI Key InChIKey=KJPZLRJLKOPGHA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20990   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20990(1-(4-{8-[butyl(ethyl)amino]-6-methyl-1H,2H,3H,4H-p...)
Affinity DataIC50: 8.20nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed