BDBM209968 US9249124, YL5-050

SMILES CN(C)c1cc(Nc2ccccc2C(O)=O)nc(Nc2ccccc2)n1

InChI Key InChIKey=DHDVEHJALGZIFE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209968   

TargetAurora kinase A(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 209968BDBM209968(US9249124, YL5-050)
Affinity DataIC50: 1.50E+4nMAssay Description:The phosphorylation of L-Hse was monitored by coupling the formation of ADP with pyruvate kinase and lactate dehydrogenase (PK/LDH). The resulting ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2017
Entry Details
US Patent

TargetAurora kinase A(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 209968BDBM209968(US9249124, YL5-050)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:Reactions were carried out at room temperature in 15 mM HEPES buffer (pH 7.4) containing 20 mM NaCl, 1 mM EGTA, 0.02% Tween 20, 10 mM MgCl2, 5% (v/v)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2017
Entry Details
US Patent