BDBM210512 US9546153, ex. 435

SMILES CC(C)(O)[C@H](F)CNC(=O)c1cnc(Nc2ccn3nccc3c2F)cc1N[C@@H]1CCCC1(F)F

InChI Key InChIKey=OASUOIJCEUEOPA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 210512   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM210512(US9546153, ex. 435)
Affinity DataIC50: 2.10nMpH: 7.2 T: 2°CAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
US Patent