BDBM210888 US9290477, 6

SMILES CO[C@H]1[C@H](C)C[C@@]2(Cc3ccc(-c4cncc(F)c4)cc3[C@@]23N=C(C)C(N)=N3)C[C@@H]1C

InChI Key InChIKey=LRKONDKPAUBJIK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 210888   

TargetBeta-secretase 1 [1-454](Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 210888BDBM210888(US9290477, 6)
Affinity DataIC50: 1.5nMpH: 4.4Assay Description:The assay was performed in the presence of OptiMEM (supernatant collected over 24 h and cleared from cellular debris by centrifugation) containing th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent