BDBM210889 US9290477, 7

SMILES CC#Cc1cncc(-c2ccc3c(c2)[C@@]2(N=C(C)C(N)=N2)[C@@]2(C3)C[C@@H](C)[C@H](OC)[C@@H](C)C2)c1

InChI Key InChIKey=HBTQOOAUHHGLEO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 210889   

TargetBeta-secretase 1 [1-454](Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 210889BDBM210889(US9290477, 7)
Affinity DataIC50: 8.20nMpH: 4.4Assay Description:The assay was performed in the presence of OptiMEM (supernatant collected over 24 h and cleared from cellular debris by centrifugation) containing th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent