BDBM21125 (5S,8R,10Z,13R)-13-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]-5-benzyl-3,6,14-trioxo-1,4,7-triazacyclotetradec-10-ene-8-carboxylic acid::Cis-H-Tyr-c[D-AllylGly-Gly-Phe-D-Allylgly]-OH::cDADAE(8)

SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CC=CC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O)C(O)=O

InChI Key InChIKey=VNZCTJLIVONUDE-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 21125   

TargetDelta-type opioid receptor(Human)
Universita Degli Studi

LigandPNGBDBM21125(Cis-H-Tyr-c[D-AllylGly-Gly-Phe-D-Allylgly]-OH | (5...)
Affinity DataKi:  0.430nM ΔG°:  -12.8kcal/mole EC50:  0.830nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2008
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Universita Degli Studi

LigandPNGBDBM21125(Cis-H-Tyr-c[D-AllylGly-Gly-Phe-D-Allylgly]-OH | (5...)
Affinity DataKi:  1.35nM ΔG°:  -12.1kcal/mole EC50:  2.35nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2008
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Universita Degli Studi

LigandPNGBDBM21125(Cis-H-Tyr-c[D-AllylGly-Gly-Phe-D-Allylgly]-OH | (5...)
Affinity DataKi:  576nM ΔG°:  -8.51kcal/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2008
Entry Details Article
PubMed