BDBM211261 US9247759, 10-9

SMILES CNC(=O)c1cccc(CN2CC(=O)N(C2=O)c2cnn(Cc3c(C)noc3C)c2)c1

InChI Key InChIKey=YOFYVHSFKVXOGD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 211261   

TargetTaste receptor type 2 member 8(Human)
Firmenich

Curated by ChEMBL
LigandPNGBDBM211261(US9247759, 10-9)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at recombinant human TAS2R8 stably expressed in cells co-expressing Galpha16gust44 assessed as inhibition of andrographolide-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTaste receptor type 2 member 8(Human)
Firmenich

Curated by ChEMBL
LigandPNGBDBM211261(US9247759, 10-9)
Affinity DataIC50: 140nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2017
Entry Details
US Patent