BDBM21194 N-[6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-(5-methylfuran-2-yl)pyrimidin-4-yl]-2-[(3R)-3-[(dimethylamino)methyl]piperidin-1-yl]acetamide::Pyrimidin-4-ylacetamide, 20

SMILES CN(C)C[C@H]1CCCN(CC(=O)Nc2cc(nc(n2)-c2ccc(C)o2)-n2nc(C)cc2C)C1

InChI Key InChIKey=KRQSPIGYXUHKMU-LJQANCHMSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 21194   

TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM21194(N-[6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-(5-methylfur...)
Affinity DataKi:  10nM ΔG°:  -10.8kcal/molepH: 7.4 T: 22°CAssay Description:The membranes prepared from Flp-In HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rat)
Neuroscience

LigandPNGBDBM21194(N-[6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-(5-methylfur...)
Affinity DataKi:  87nM ΔG°:  -9.53kcal/molepH: 7.4 T: 22°CAssay Description:The membranes prepared from Flp-In HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Human)
Neuroscience

LigandPNGBDBM21194(N-[6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-(5-methylfur...)
Affinity DataKi:  890nMAssay Description:The membranes prepared from Flp-In HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed