BDBM212281 US9290507, I-1

SMILES CN1CCN(CC1)c1cncc(c1)-c1cn(nn1)-c1cc(ccc1C)C(=O)Nc1cc(on1)C(C)(C)C

InChI Key InChIKey=DRRAGFXUNAAEDE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 212281   

TargetSerine/threonine-protein kinase B-raf(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM212281(US9290507, I-1)
Affinity DataIC50: 8nMpH: 7.5Assay Description:In a dilution series 10 uL/well of test substance solution are placed in a multiwell plate. The dilution series is selected so that generally a range...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
US Patent