BDBM212351 US9290507, I-71

SMILES Cc1ccc(cc1-n1cc(nn1)-c1cncc(c1)N1C[C@@H]2C[C@H]1CN2)C(=O)Nc1cc(ccn1)C(F)(F)F

InChI Key InChIKey=PFPOPNWNTZLCJA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 212351   

TargetSerine/threonine-protein kinase B-raf(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM212351(US9290507, I-71)
Affinity DataIC50: 4nMpH: 7.5Assay Description:In a dilution series 10 uL/well of test substance solution are placed in a multiwell plate. The dilution series is selected so that generally a range...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
US Patent