BDBM212480 BDBM212505::US10155731, Example 63::US9278944, 31

SMILES COCCCn1cc(Cl)c2ccc(cc12)[C@H](C)N(C1CC1)C(=O)[C@H]1CNCCN1

InChI Key InChIKey=UHYIJJQHEZOFOU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 212480   

TargetRenin(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 212480BDBM212480(US9278944, 31 | BDBM212505 | US10155731, Example 6...)
Affinity DataIC50: 580nMAssay Description:A substrate of synthetic peptide (Nma-KHPFHLVIHK(Dnp)-NH2) and test compound were mixed, and fluorescence intensity was assayed using a fluorophotome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2017
Entry Details
US Patent

TargetRenin(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 212480BDBM212480(US9278944, 31 | BDBM212505 | US10155731, Example 6...)
Affinity DataIC50: 580nMAssay Description:A substrate of synthetic peptide (Nma-KHPFH LVIHK(Dnp)-NH2) and test compound were mixed, and fluorescence intensity was assayed using a fluorophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetRenin(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 212480BDBM212480(US9278944, 31 | BDBM212505 | US10155731, Example 6...)
Affinity DataIC50: 800nMAssay Description:A substrate of synthetic peptide (Nma-KHPFH LVIHK(Dnp)-NH2) and test compound were mixed, and fluorescence intensity was assayed using a fluorophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetRenin(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 212480BDBM212480(US9278944, 31 | BDBM212505 | US10155731, Example 6...)
Affinity DataIC50: 800nMAssay Description:A substrate of synthetic peptide (Nma-KHPFHLVIHK(Dnp)-NH2) and test compound were mixed, and fluorescence intensity was assayed using a fluorophotome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2017
Entry Details
US Patent