BDBM213365 US9278976, (3S,5R)-5-[1-(cyclopentanesulfonyl)-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-5-yl]-2-(2,4,5-trifluorophenyl)oxan-3-amine

SMILES N[C@H]1C[C@H](COC1c1cc(F)c(F)cc1F)N1Cc2cnn(c2C1)S(=O)(=O)C1CCCC1

InChI Key InChIKey=HQRVCZSAVCSZFT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 213365   

TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM213365(US9278976, (3S,5R)-5-[1-(cyclopentanesulfonyl)-1H,...)
Affinity DataIC50: 2.60nMpH: 7.5 T: 2°CAssay Description:A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent