BDBM213655 US9278981, 247
SMILES FC(F)(Cl)Oc1ccc(NC(=O)c2cnc(N3CCC(F)(F)C3)c(c2)-c2cncnc2)cc1
InChI Key InChIKey=QYCPMMHFZSTIFJ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 213655
Affinity DataIC50: <0.130nMpH: 7.5 T: 30°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMpH: 7.5 T: 25°CAssay Description:For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-...More data for this Ligand-Target Pair