BDBM213721 US9284284, 12

SMILES Cc1cn2ccnc(Nc3ccc(F)c(c3)[C@@]3(COCC(N)=N3)C(F)F)c2n1

InChI Key InChIKey=SVCVFKHLSFFKPD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 213721   

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM213721(US9284284, 12)
Affinity DataIC50: 72nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 1 nM concentrations is incubated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM213721(US9284284, 12)
Affinity DataIC50: 350nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 1 nM concentrations is incubated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent