BDBM213786 US9284315, 58

SMILES COc1ccc(cn1)-c1ccc2ncc3CN(C)C(=O)N(c4ccc(N5CCNCC5)c(c4)C(F)(F)F)c3c2n1

InChI Key InChIKey=YGICWJPNLJZODT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 213786   

LigandPNGBDBM213786(US9284315, 58)
Affinity DataIC50: 8.60nMpH: 7.5 T: 2°CAssay Description:1. Preparation of test reagents{circle around (1)} 1x kinase buffer (50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, 100 mM NaCl, 0.03% CHAPS, 2 mM DTT);...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Zuanzhu Pharma

US Patent
LigandPNGBDBM213786(US9284315, 58)
Affinity DataIC50: 91.9nMpH: 7.5 T: 2°CAssay Description:1. Preparation of test reagents {circle around (1)} 1x kinase buffer (50 mM HEPES, pH 7.5, 10 mM MgCl2, 1 mM EGTA, 3 mM MnCl, 0.01% Tween-20, 2 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent