BDBM213788 US9284315, 114

SMILES COc1ccc(cn1)-c1ccc2ncc3CN(C)C(=O)N(C4CCNCC4)c3c2n1

InChI Key InChIKey=MAGROAXLRFHEQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 213788   

LigandPNGBDBM213788(US9284315, 114)
Affinity DataIC50: 115nMpH: 7.5 T: 2°CAssay Description:1. Preparation of test reagents{circle around (1)} 1x kinase buffer (50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, 100 mM NaCl, 0.03% CHAPS, 2 mM DTT);...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Zuanzhu Pharma

US Patent
LigandPNGBDBM213788(US9284315, 114)
Affinity DataIC50: 732nMpH: 7.5 T: 2°CAssay Description:1. Preparation of test reagents {circle around (1)} 1x kinase buffer (50 mM HEPES, pH 7.5, 10 mM MgCl2, 1 mM EGTA, 3 mM MnCl, 0.01% Tween-20, 2 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent