BDBM214348 US9283222, 411

SMILES CC1(C)O[C@@H]2[C@H](O1)[C@@H]1C[C@H]2N(c2cc(Cc3n[nH]c(=O)c4c3CCCC4)ccc2F)C1=O

InChI Key InChIKey=VLFTZHJGWPHSFW-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 214348   

TargetPoly [ADP-ribose] polymerase 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 214348BDBM214348(US9283222, 411)
Affinity DataKi:  8nMpH: 8.0Assay Description:PARP1 assay was conducted in PARP assay buffer containing 50 mM Tris pH 8.0, 1 mM DTT, 4 mM MgCl2. PARP reactions contained 1.5 uM [3H]-NAD+ (1.6 uCi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2017
Entry Details
US Patent