BDBM214647 US10688093, Compound BF000817099::US11701353, Compound BF000817099::US9284319, R5::US9730929, Example R5::US9783543, R5

SMILES C1CC(CCO1)Nc1ccc2ncc(-c3ccncc3)n2n1

InChI Key InChIKey=UUVPHDJCRCLZOZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 214647   

LigandPNGBDBM214647(US9284319, R5 | US9730929, Example R5 | US9783543,...)
Affinity DataIC50: 192nMpH: 7.5 T: 2°CAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2017
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM214647(US9284319, R5 | US9730929, Example R5 | US9783543,...)
Affinity DataIC50: 192nMAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetTyrosine-protein kinase Fyn(Human)
Pathways Neuro Pharma

US Patent
LigandPNGBDBM214647(US9284319, R5 | US9730929, Example R5 | US9783543,...)
Affinity DataIC50: 270nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM214647(US9284319, R5 | US9730929, Example R5 | US9783543,...)
Affinity DataIC50: 480nMAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

LigandPNGBDBM214647(US9284319, R5 | US9730929, Example R5 | US9783543,...)
Affinity DataIC50: 480nMpH: 7.5 T: 2°CAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2017
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM214647(US9284319, R5 | US9730929, Example R5 | US9783543,...)
Affinity DataIC50: 480nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
US Patent