BDBM214942 US9296734, 220

SMILES CC(C)(C)OC(=O)N(C(=O)c1ccccc1)C1=N[C@@](CF)(C[C@H](O1)C(F)(F)F)c1cc(Br)cnc1F

InChI Key InChIKey=AZADPTMTRMDTQW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 214942   

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM214942(US9296734, 220)
Affinity DataIC50: 429nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent