BDBM215110 US9296736, 61::US9593129, Example 61

SMILES Cc1cc(C[C@@H]2C[C@@H]([C@H](N(CC3CC3)C2=O)c2ccc(Cl)cc2)c2cccc(Cl)c2)no1

InChI Key InChIKey=BASWMXRPLQGFOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 215110   

LigandChemical structure of BindingDB Monomer ID 215110BDBM215110(US9296736, 61 | US9593129, Example 61)
Affinity DataIC50: 310nMpH: 7.4 T: 2°CAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [1-188](Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 215110BDBM215110(US9296736, 61 | US9593129, Example 61)
Affinity DataIC50: 310nMAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2019
Entry Details
US Patent